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On May 2nd of this year, Ningbo City mobilized and deployed a special action to implement the strategy of "walking on the front line with big feet and breaking through difficulties with small teams", among which accelerating the creation of the Zhejiang Southeast National Independent Innovation Demonstration Zone was listed as one of the key projects. How to make efforts to establish the Zhejiang Southeast National Independent Innovation Demonstration Zone? Recently, reporters have been following up on this matter.

The executive meeting of the State Council held on March 30, 2016, clearly designated Ningbo as a key cultivation target for the national independent innovation demonstration zone. With Ningbo National High tech Zone as the core, in conjunction with Wenzhou National High tech Zone, it will radiate and drive Zhoushan and Taizhou, and jointly build the Zhejiang Southeast National Independent Innovation Demonstration Zone.

The southeastern region of Zhejiang has convenient sea and land transportation, serving as China's "eastern gateway" and an important hub of the Maritime Silk Road. It is also one of the most active areas for foreign trade and exchanges in China. In 2016, the total GDP of Ningbo, Wenzhou, Taizhou, and Zhoushan was 1.86 trillion yuan, accounting for 40.1% of the total GDP of Zhejiang Province.

Li Yonghui, Director of the Science and Technology Bureau of Ningbo City, stated in an interview with reporters that Ningbo will make every effort to promote the creation of the Zhejiang Southeast National Independent Innovation Demonstration Zone, providing strong technological support for the construction of Ningbo as a "famous city and capital" and becoming one of the top cities in China. He said that the science and technology department will focus on the overall position of "strengthening the main position of private enterprises in entrepreneurship and innovation, and creating a new highland for innovation and entrepreneurship in the private economy", with "promoting innovation and entrepreneurship in the private economy, seeking new driving forces for new economic development" as the main line, optimizing the allocations of innovative resources such as talent, capital, and technology, accelerating the cultivation of the science and technology entrepreneurship team, the development of the new materials industry, and the optimization of the innovation ecological environment, and carrying out reform pilot projects in talent special zones, science and technology financial innovation, and the transformation of scientific and technological achievements.

The Zhejiang Southeast National Independent Innovation Demonstration Zone relies on the Ningbo National High tech Zone, which currently gathers half of Ningbo's key scientific and technological research and development institutions and public technology service platforms. It has been listed as a national innovation oriented science and technology park and a national overseas high-level talent entrepreneurship and innovation base, becoming the core area for implementing the innovation driven development strategy in Ningbo.

How should the ratio of the original solution be matched? "" In terms of drying technology, which solution is better, oven baking or room temperature self drying? "Two technicians from Ningbo Beifa Company, who make" China's Good Pen, "walked into Guo's office to discuss the production formula and process of painting the pen holder with him.

At present, traditional solvent based coatings occupy the vast majority of the market share, and the trend of water-based industrial paint is determined! "Yu Guo, a member of the National Water based Industrial Paint Coating Committee with 10 years of experience in chemical production, confidently stated that water-based paint, as a new high-tech product, is a product that replaces or overturns traditional solvent based paints. The water-based paint is disrupting a huge market with an annual trading volume of 400 billion yuan. Its market prospects are definitely enormous

A high-tech entrepreneurial team settled in Ningbo National High tech Zone (New Materials Science and Technology City) is trying this "subversion".

The team's goal is very clear - to develop a safe, environmentally friendly, and pollution-free coating material and formula, reduce the harm and pollution caused by organic solvents to the environment, ensure the health of operators, reduce the production cost of coatings, facilitate factory safety measures and transportation, and also facilitate tool cleaning.

"What we do is not paint, but the core raw materials of paint, just like a company that focuses on the production of computer CPUs rather than computers." Whenever it comes to the company's research and development projects, President Yu Guo likes to cite the example of pork, "We sell meat, and through the cultivation and inspection of high-quality food materials, we ensure the health, safety and taste of meat from the source! But as for fried meat or Braised pork belly, how to prepare dishes and how to cook depends on the needs and preferences of diners."

In short, developing high-performance air drying self crosslinking water-based resins - water+vegetable oil=bio based environmentally friendly water-based coatings - can be regarded as the "organic food" in the paint industry, truly achieving non-toxic and harmless paint. Yu Guo is confident that the implementation of the project will drive a large number of industries across the country to shift towards green and environmentally friendly coating.

At the 3rd Global New Materials Industry Competition in Ningbo, China, which ended in September 2016, the project "Research and Sales of Air drying Self crosslinking Water based Resin" won the special prize. Some judges believe that if the project can be successfully launched, it will disrupt the traditional paint market. If all types of paints in the country are replaced by water-based paints, it will completely overturn the existing 800 billion yuan paint market capacity.

As a result, the company received angel investment of 6 million yuan in financing. Founder Yu Guo revealed that this is the first "huge" investment received by the team after registering with an initial investment of 2 million yuan, and also the first "funding" received when they came to Ningbo. This brings us great confidence

Changmu (Ningbo) New Material Technology Co., Ltd. was established in July 2016. Master's, doctoral, postdoctoral, professor and other professionals in the entrepreneurial team will form an entrepreneurial team led by Professor Cui Wenguo, introduce overseas personnel as the core technology of the team, and establish a 5-person entrepreneurial team.

Yu Guo said that the mature industrial chain in the local area is an important consideration for the development of enterprise settlement. The strong foundation of the new materials industry in Ningbo and the superior entrepreneurial environment of the National High tech Zone (New Materials Science and Technology City) are important reasons for attracting entrepreneurial teams to settle in Ningbo

Zhang Hao, a Ph.D. in Biomaterials from Oxford University in the UK, was also attracted by the "soft environment". As the fifth batch of "3315 Plan" entrepreneurial talents in 2015, Zhang Hao founded Ningbo Vivid Cell Technology Co., Ltd. in April 2016 and settled in Ningbo Yinzhou Science and Technology Information Incubation Park.

If immune cell therapy, as one of the directions of cell therapy, has shown people the possibility of overcoming cancer and tumors, then as another direction of cell therapy, stem cells have shown hope in the treatment of various diseases such as hematological diseases, neurological diseases, cardiovascular diseases, autoimmune diseases, and endocrine diseases.

We hope to provide standardized, simplified, and scaled up automated cell separation and cultivation equipment to provide patients with efficient, affordable, and precise new medical methods. "Zhang Hao led a team to Ningbo with cutting-edge technology from Oxford University and the UK Advanced Manufacturing Research Center for Regenerative Medicine, and they are using small cells to create a powerful force of magic.

Zhang Hao compared the new bioreactor developed by the team to a "cell production line": it has automated module functions such as cell planting, expansion, directed differentiation, and cell quantity and quality detection, and can standardize the cell culture process. At present, the prototype of this product has been born.

Many foreign devices are originally designed for large-scale cell culture preparation, so a large amount of culture medium is used in the reactor every time, resulting in waste of such consumables, "Zhang Hao said." Our developed products are more compact in size. Moreover, domestic machines will be cheaper in price, at least reducing cell production costs by 50%. "Currently, imported bioreactors with similar product efficacy are priced at 2 to 3 times higher. This reactor is currently applying for a patent and is expected to achieve mass production this year.

Cell therapy is an emerging industry. At present, in the field of cell therapy in China, more emphasis is placed on cell storage, such as the storage of umbilical cord blood for infants. However, the coverage of downstream cell therapy applications is not extensive. When a person needs cell therapy, they only need to process their stored cells or qualified cells donated by others through an automated production line, and then they can use them, "Zhang Hao confidently told reporters.

Zhang Hao revealed to reporters that the company has also been shortlisted for the "2017 Top 40 Most Valuable Investment Enterprises in Ningbo". The companies that advance to the top 40 will connect with more than 3000 well-known investment institutions in China and have the opportunity to connect with global capital.